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清华大学学报(自然科学版)  2014, Vol. 54 Issue (2): 172-177    
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中国人颈椎间盘尺寸分析
刘伟强1,2,3(),蒲婷1,2,顾洪生4,廖振华2,姜锦鹏3
2. 深圳清华大学研究院, 深圳 518057
3. 清华大学 生物医学工程系, 北京100084
4. 深圳市第二人民医院, 深圳 518049
Geometric parameter analysis of Chinese cervical discs
Weiqiang LIU1,2,3(),Ting PU1,2,Hongsheng GU4,Zhenhua LIAO2,Jinpeng JIANG3
1. Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China
2. Research Institute of Tsinghua University in Shenzhen, Shenzhen 518057, China
3. Department of Biomedical Engineering, Tsinghua University, Beijing 100084, China
4. Shenzhen Second People's Hospital, Shenzhen 518049, China
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摘要 

为了给基于中国人骨骼特征的人工颈椎间盘假体关键尺寸设计及人工颈椎间盘置换术假体型号选择提供理论参考,该文制定了一套严格的颈椎间盘尺寸测量方法,利用正常中国人颈椎磁共振成像(MRI)数据,测量1 600例中国人颈椎C23、 C34、 C45、 C56、 C67全5个颈椎间盘的6项尺寸参数(前高、中高、后高、椎间角、矢径、横径), 统计分析中国人颈椎间盘尺寸特点。结果显示: 正常中国人颈椎间盘高度随年龄的增加出现先增加后降低的趋势,在年龄组39~48岁存在极大值。颈椎间盘节段自上而下,6项尺寸参数值均相应增大,且除椎间角呈指数规律变化外,其他各参数均具有明显的线性相关性。同时,女性颈椎间盘各项尺寸约为男性相应尺寸90%。

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刘伟强
蒲婷
顾洪生
廖振华
姜锦鹏
关键词 颈椎间盘磁共振成像(MRI)尺寸测量人工颈椎间盘    
Abstract

A protocol is developed for precise measurements of the geometric parameters of cervical discs as a basis for the design of artificial cervical discs for Chinese people and the selection of total disc replacement models. The six key parameters (i.e., the anterior height, the middle height, the posterior height, the intervertebral angle, the sagittal diameter and the transverse diameter) of all the five cervical intervertebral discs, C23, C34, C45, C56 and C67, are measured from a magnetic resonance imaging (MRI) database of normal Chinese discs. Chinese cervical disc geometric characteristics are then analyzed statistically. The height of a normal Chinese cervical disc tends to increase first and then decrease with age, with the maximum at 39-48 years old. All six parameters increase about linearly from the upper to the lower discs except for the intervertebral angle. The parameters for females are about 90% of those for males.

Key wordscervical disc    magnetic resonance imaging (MRI)    geometric parameter measurement    artificial cervical disc
收稿日期: 2013-06-07      出版日期: 2015-04-16
ZTFLH:     
基金资助:国家“十二五”科技支撑计划项目 (2012BAI18B05);深圳市技术创新计划 (CXZZ20130322171346982)
引用本文:   
刘伟强, 蒲婷, 顾洪生, 廖振华, 姜锦鹏. 中国人颈椎间盘尺寸分析[J]. 清华大学学报(自然科学版), 2014, 54(2): 172-177.
Weiqiang LIU, Ting PU, Hongsheng GU, Zhenhua LIAO, Jinpeng JIANG. Geometric parameter analysis of Chinese cervical discs. Journal of Tsinghua University(Science and Technology), 2014, 54(2): 172-177.
链接本文:  
http://jst.tsinghuajournals.com/CN/  或          http://jst.tsinghuajournals.com/CN/Y2014/V54/I2/172
  椎间盘尺寸测量示意图(矢状面)
  椎间盘尺寸测量示意图(横断面)
年龄/岁 男性 女性
样本量 (平均年龄±
标准差)/岁
样本量 (平均年龄±
标准差)/岁
16~28 180 24.67±2.75 164 25.17±2.90
29~38 264 33.46±3.02 314 33.36±2.82
39~48 233 42.49±2.78 258 42.95±2.72
49~58 39 52.31±2.60 92 52.59±3.06
59~68 21 62.05±2.85 32 62.97±3.14
  样本年龄分布统计
  颈椎间盘高度(AH、 MH、 PH)随年龄变化趋势(M: 男性; F: 女性)
  颈椎间盘各尺寸随节段变化趋势(M: 男性; F: 女性)
尺寸参数 男性 女性
AH/mm 0.25n+3.05 0.23n+2.68
MH/mm 0.21n+4.72 0.22n+4.22
PH/mm 0.07n+2.67 0.08n+2.37
IVA/(°) 0.60 exp(n/3.08)+2.23 1.61 exp(n/5.90)+0.10
S/mm 0.45n+14.87 0.37n+13.51
T/mm 1.39n+19.22 1.41n+17.16
  颈椎间盘尺寸变化规律 (n为节段代号, n=1代表C23, …, n=5代表C67)
节段 女性尺寸与男性尺寸的比值/%
AH MH PH IVA S T
C23 86.90 90.69 89.76 95.46 90.02 88.69
C34 89.83 90.60 90.14 96.18 90.09 90.91
C45 89.81 90.65 89.95 95.92 90.50 91.60
C56 88.40 91.58 91.40 95.12 89.61 92.37
C67 89.24 92.65 92.25 90.02 89.48 92.00
  女性颈椎间盘尺寸与男性相应尺寸的比值
节段 男性 女性
C23 81.55 71.46
C34 68.89 70.35
C45 74.19 76.32
C56 84.81 80.07
C67 84.07 85.94
  IVA计算值与测量值的比值%
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