ENGINEERING PHYSICS |
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Simulation of strategies for large-scale spread containment of infectious diseases |
NI Shunjiang, WENG Wenguo, ZHANG Hui |
Institute of Public Safety Research, Department of Engineering Physics, Tsinghua University, Beijing 100084, China |
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Abstract This paper investigates the inhibitory effects of four typical containment strategies, including quarantine, contact tracing, antiviral prophylaxis and vaccination, on the transmission process of infectious diseases. A large-scale individual-based simulation model for the spread of infectious diseases was built based on the complex network theory, with the containment strategies mentioned above then introduced into the model by quantifying the model parameters to rebuild an epidemic model. Simulation results show that these containment strategies can effectively inhibit the spread of infectious diseases, with the implementation cost significantly reduced through optimal combination of the containment strategies. The results can generate insights into scientific decision-making in the prevention and control of infectious disease spread for the public health sector.
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Keywords
large-scale epidemic spreading
epidemic modeling
containment strategy
complex network
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Issue Date: 15 January 2016
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