|
|
| Guide |
|
|
Abstract Before tumor thermoseed mediated magnetic induction hyperthermia can be used, in vivo 3-D treatment models and temperature distributions in the target region should be numerically simulated to ensure the curative efficacy and to prevent overheating of normal tissues. This paper uses Ni-Cu alloy thermoseeds as the implanted medium in a heating model using the Pennes equation discretized by the finite volume method to study the steady-state temperature distributions for different thermoseed arrangements. The model predicts the temperature fluctuation and effective treatment areas for different blood perfusions. These results show that the preoperative thermoseed arrangement planning and the bio-tissue blood perfusion rate are both key factors to determine the steady-state temperature distributions. This paper provides guidelines for reasonable preoperative treatment planning for magnetic induction hyperthermia.
|
| Keywords
ferromagnetic thermoseed
magnetic induction hyperthermia
steady-state temperature distributions
finite volume method
3-D simulations
|
|
|
| Fund: |
|
Issue Date: 15 May 2014
|
|
|
| [1] |
唐劲天. 肿瘤热疗生物学 [M]. 北京: 人民卫生出版社, 2010: 221-228, 268-275. TANG Jintian. Tumor Hyperthermia Biology [M]. Beijing: People’s Medical Publishing House, 2010: 221-228, 268-275. (in Chinese)
|
| [2] |
王捷忠, 潘建基, 张春, 等. 关于磁感应热疗技术治疗软组织肿瘤近期疗效和安全性的临床报告[J]. 福建医科大学学报, 2012, 46(1): 47-50. WANGJiezhong, PAN Jianji, ZHANG Chun, et al.A clinical report on effectiveness and safety of magnetic induction thermotherapy for soft tissue tumor[J]. Journal of Fujian Medical University, 2012, 46(1): 47-50. (in Chinese)
|
| [3] |
雷庆春, 乐恺, 张欣欣. 金属支架用于食管肿瘤局部热疗的温度场数值模拟[J]. 中国生物医学工程学报, 2011, 5(30): 712-717. LEI Qingchun, YUE Kai, ZHANG Xinxin. Numerical simulation of heat transfer for esophageal cancer hyperthermia with a heatable metal stent[J]. Chinese Journal of Biomedical Engineering, 2011, 5(30): 712-717. (in Chinese)
|
| [4] |
Li Z, Kawamura K, Kawashita M, et al.In vitro assessment of poly(methylmethacrylate)-based bone cement containing magnetite nanoparticles for hyperthermia treatment of bone tumor[J]. Journal of Biomedical Materials Research, 2012, 10(100): 2537-2861.
|
| [5] |
Sadhukha T, Wiedmann T S, Panyam J. Inhalable magnetic nanoparticles for targeted hyperthermia in lung cancer therapy[J]. Biomaterials, 2013, 21(34): 5163-5171.
|
| [6] |
Chen Z P. Three-dimensional simulations of ferromagnetic implant hyperthermia[J]. Medical Physics, 1992, 19(4): 989-997.
url: http://dx.doi.org/10.1118/1.596787
|
| [7] |
Tompkins D T, Vanderby R, Klein S A, et al.Effect of interseed spacing, tissue perfusion, thermoseed temperatures and catheters in ferromagnetic hyperthermia: Results from simulations using finite element models of thermoseeds and catheters[J]. IEEE Transactions on Biomedical Engineering, 1994, 41(10): 975-985.
url: http://dx.doi.org/10.1109/10.324530
|
| [8] |
Dughiero F, Corazza S. Numerical simulation of thermal disposition with induction heating used for oncological hyperthermic treatment[J].Medical & Biological Engineering & Computing, 2005, 43: 40-46.
|
| [9] |
Haider S A, Wait J R, Cetas T C, et al.Power absorption in ferromagnetic implants from radio frequency magnetic fields and the problem of optimization[J]. IEEE Transactions on Microwave Theory and Techniques, 1991, 39(11): 1817-1827.
url: http://dx.doi.org/10.1109/22.97482
|
| [10] |
Pennes H H. Analysis of tissue and arterial blood temperature in the resting forearm[J], Journal of Applied Physiology, 1948, 1(2): 93-122.
|
| [11] |
Liu J. Uncertainty analysis for temperature prediction of biological bodies subject to randomly spatial heating[J].Journal of Biomechanics, 2001, 34: 1637-1642.
url: http://dx.doi.org/10.1016/S0021-9290(01)00134-8
|
| [12] |
李人宪. 有限体积法基础 [M]. 第2版. 北京: 国防工业出版社, 2008: 15-35. LI Renxian. Basis of Finite Volume Method [M]. 2nd Ed. Beijing: National Defense Industry Press, 2008: 15-35. (in Chinese)
|
| [13] |
孟萃, 唐劲天, 程建平, 等. 铁磁热籽热疗中温度场稳态分布的三维数值研究 [C]// 第十一届中国体视学与图像分析学术年会. 宁波: 中国体视学学会, 2006: 505-509. MENG Cui, TANG Jintian, CHENG Jianping, et al.Three- dimensional simulation of the temperature research for ferromagnetic hyperthermia [C]// The 11th Chinese Conference of Stereology and Image Analysis. Ningbo: Chinese Society for Stereology, 2006: 505-509. (in Chinese)
|
| [14] |
邓中山, 刘静. 肿瘤热疗计划中三维温度分布的不确定性研究[J]. 工程热物理学报, 2004, 25(4): 664-666. DENG Zhongshan, LIU Jing. Uncertainty analysis of 3-D temperature distribution during treatment planning of tumor hyperthermia[J].Journal of Engineering Thermophysics, 2004, 25(4): 664-666. (in Chinese)
url: http://118.145.16.217/magsci/article/article?id=17448851
|
| [15] |
刘静, 邓中山. 肿瘤热疗物理学 [M]. 北京: 科学出版社, 2008: 34-37. LIU Jing, DENG Zhongshan. Physics of Tumor Hyperthermia [M]. Beijing: Science Press, 2008: 34-37. (in Chinese)
|
| [16] |
Zhai W, Xu J, Zhao Y, et al.Preoperative surgery planning for percutaneous hepatic microwave ablation [C]// Medical Image Computing and Computer-Assisted Intervention— MICCAI 2008. New York, USA: Springer Press, 2008, 569-577.
|
| [17] |
翟伟明, 盛林, 宋亦旭, 等. 基于影像引导的计算机辅助肝癌微波消融[J]. 计算机研究与发展, 2011, 48(2): 281-288. ZHAI Weiming, SHENG Lin, SONG Yixu, et al.Image guided computer assisted microwave ablation for liver cancer[J].Journal of Computer Research and Development, 2011, 48(2): 281-288. (in Chinese)
url: http://118.145.16.217/magsci/article/article?id=19161628
|
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
Cited |
|
|
|
|
| |
Shared |
|
|
|
|
| |
Discussed |
|
|
|
|
2014,
Vol. 54
)
