| BIOLOGICAL SCIENCE AND ENGINEERING |
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Fast CAPs threshold and tuning curves based on a sound card detection system |
| GONG Qin, ZHANG Shuoyue |
| Department of Biomedical Engineering, Tsinghua University, Beijing 100084, China |
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Abstract Auditory nerve compound action potentials (CAPs) threshold curves reflect the hearing sensitivity to intensity variations while its tuning curves reflect the sensitivity to frequency variations in the auditory nerve system. A fast CAPs threshold and tuning curve detection algorithm were developed based on an external multimedia sound card with C# to simplify the data extraction for studies of the auditory nerve system with more objective and more accurate information in a shorter time. The factors influencing the fast CAPs tuning curves such as the orientation of the sweeping frequency and the frequency of the stimulus were analyzed using guinea pig experiments. The fast CAPs threshold and tuning curves compare well with previous results. The factors contributing to fast CAPs tuning curve accuracy include reduction of the needed criteria and the rates of change for the masker intensity. This system is a fast, objective, and comprehensive analysis platform which will be valuable for further research on auditory nerve compound action potentials.
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| Keywords
compound action potentials (CAPs)
threshold curves
tuning curves
fast method
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Issue Date: 15 September 2015
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[1] Pickles J O. An Introduction to the Physiology of Hearing [M]. 2nd Ed. London, UK: Academic Press Inc, 1988.
[2] Dallos P, Cheatham M A. Compound action potential (AP) tuning curves [J]. Journal of the Acoustical of Society of America, 1976, 59 (3): 591-597.
[3] Harrison R V, Aran J M, Erre J P. AP tuning curves from normal and pathological human and guinea pig cochleas [J]. Journal of the Acoustical of Society of America, 1981, 69 (5): 1374-1385.
[4] Eggermont J J. Compound action potential tuning curves in normal and pathological human ears [J]. Journal of the Acoustical of Society of America, 1977, 62(5): 1247-1251.
[5] Ruggero M A, Temchin A N. Unexceptional sharpness of frequency tuning in the human cochlea [J]. Proceedings of the National Academy of Sciences of the United States of America, 2005, 102(51): 18614-18619.
[6] Salt A N, Garcia P. Cochlear action potential tuning curves recorded with a derived response technique [J]. Journal of the Acoustical of Society of America, 1990, 88(3): 1392-1402.
[7] 宫琴, 黎婷婷, 刘帅. 一种基于声卡的 CAPs 检测系统的研制 [J]. 清华大学学报: 自然科学版, 2014, 54(5): 678-684.GONG Qin, LI Tingting, LIU Shuai. Development of a sound card-based CAPs detection system [J]. Journal of Tsinghua University: Science and Technology, 2014, 54(5): 678-684. (in Chinese)
[8] Sek A, Alcántara J, Moore B C J, et al. Development of a fast method for determining psychophysical tuning curves: Desarrollo de un método rápido para determinar curvas psicofísicas de sintonía [J]. International Journal of Audiology, 2005, 44(7): 408-420.
[9] Eggermont J J. Analysis of compound action potential responses to tone bursts in the human and guinea pig cochlea [J]. The Journal of the Acoustical Society of America, 1976, 60(5): 1132-1139.
[10] 宫琴. 生物医学工程检测和基础实验 [M]. 北京: 清华大学出版社, 2013. GONG Qin. Biomedical Engineering Detection and Basic Experimenting [M]. Bejing: Tsinghua University Press, 2013. (in Chinese)
[11] 张家騄. 听觉部位学说与频率差阈[J]. 声学学报, 2006, 31(2): 97-100.ZHANG Jialu. On the place theory and the frequency difference limen of hearing [J]. Acta Acustica, 2006, 31(2): 97-100. (in Chinese)
[12] 顾瑞. 临床听力学 [M]. 北京: 中国协和医科大学出版社, 2008. GU Rui. Clinical Audiology [M]. Beijing: Peking Union Medical College Press, 2008. (in Chinese)
[13] McMahon C M, Patuzzi R B. The origin of the 900 Hz spectral peak in spontaneous and sound-evoked round-window electrical activity [J]. Hearing Research, 2002, 173(1): 134-152. |
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2015,
Vol. 55
