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清华大学学报(自然科学版)  2015, Vol. 55 Issue (6): 700-704    
  生物与生物医学 本期目录 | 过刊浏览 | 高级检索 |
980 nm脉冲激光诱发听神经冲动
关添1, 吴默村1,2, 朱凯1,2, 王健3
1. 清华大学 深圳研究生院, 生物医学工程研究中心, 深圳 518055;
2. 清华大学 生物医学工程系, 北京 100084;
3. 深圳信息职业技术学院 电子与通信学院, 深圳 518172
980 nm pulsed laser-induced auditory nerve impulses
GUAN Tian1, WU Mocun1,2, ZHU Kai1,2, WANG Jian3
1. Research Center of Biomedical Engineering, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, China;
2. Department of Biomedical Engineering, Tsinghua University, Beijing 100084, China;
3. Electronics and Communication College, Shenzhen Institute of Information Technology, Shenzhen 518172, China
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摘要 为了最优化选取刺激人工耳蜗激光参数,该文选用波段980 nm脉冲激光刺激豚鼠听神经,成功诱发了光刺激复合动作电位(optical compound action potentials, oCAPs); 通过分析实验结果表明: 光刺激具有一定的安全性,其刺激强度不是越大越好,存在一个最佳区域范围。
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关添
吴默村
朱凯
王健
关键词 人工耳蜗近红外激光光刺激光质复合动作电位(oCAPs)    
Abstract:A 980 nm near infrared laser was used to stimulate the auditory nerve in guinea pig cochlea to provide useful optical parameters for the development of an optical cochlear implant. The 980 nm pulsed laser can evoke optical compound action potentials (oCAPs) from guinea pig cochlea. The experimental results also demonstrate the security of optical stimulus and larger optical intensities not always giving better results.
Key wordscochlear implant    near infrared laser    optical stimulation    optical compound action potentials (oCAPs)
收稿日期: 2015-01-07      出版日期: 2015-09-08
ZTFLH:  R318.6  
引用本文:   
关添, 吴默村, 朱凯, 王健. 980 nm脉冲激光诱发听神经冲动[J]. 清华大学学报(自然科学版), 2015, 55(6): 700-704.
GUAN Tian, WU Mocun, ZHU Kai, WANG Jian. 980 nm pulsed laser-induced auditory nerve impulses. Journal of Tsinghua University(Science and Technology), 2015, 55(6): 700-704.
链接本文:  
http://jst.tsinghuajournals.com/CN/  或          http://jst.tsinghuajournals.com/CN/Y2015/V55/I6/700
  图1 光学平台示意图
  图2 豚鼠耳蜗示意图
  图3 声刺激CAP和光刺激oCAPs比较
  图4 光刺激强度与oCAPs幅值的关系
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